Main Title |
Effect of Methyl Linoleate Hydroperoxide (MLHP), A Possible Toxic Intermediate of Ozone, on Human Normal and Glucose-6-Phosphate Dehydrogenase (G-6-PD) Deficient Erythrocytes. |
Author |
Williams, P. S. ;
Calabrese, E. J. ;
Moore, G. S. ;
|
CORP Author |
Massachusetts Univ., Amherst. Dept. of Public Health.;Health Effects Research Lab., Research Triangle Park, NC. |
Year Published |
1983 |
Report Number |
EPA-R-805797; EPA/600/J-83/277; |
Stock Number |
PB85-177855 |
Additional Subjects |
Erythrocytes ;
Ozone ;
In vitro analysis ;
Air pollution ;
Oxidation ;
Chemical reactions ;
Public health ;
Exposure ;
Reprints ;
Chemical reaction mechanisms ;
Air pollution effects(Humans) ;
Dehydrogenase/glucose-phosphate ;
Linoleic acid/(methyl-ester)-hydroperoxy
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB85-177855 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
14p |
Abstract |
Erythrocytes of both normal and G-6-PD deficient humans responded in a dose-dependent manner to the oxidant stress of MLHP as measured by decreases in G-6-PD activity, increases in methemoglobin (METHB) levels and decreases in reduced glutahione (GSH). The G-6-PD deficient erythrocytes displayed a markedly enhanced sensitivity to MLPH induced decreases in G-6-PD activity and METHB increases while being less sensitive than normal erythrocytes to changes in GSH levels. (Copyright (c) 1983 by Marcel Dekker, Inc.) |
Availability Notes |
Pub. in Jnl. of Environmental Science and Health, A18 n1 p37-49 1983. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Effect of Methyl Linoleate Hydroperoxide (MLHP), A Possible Toxic Intermediate of Ozone, on Human Normal and Glucose-6-Phosphate Dehydrogenase (G-6-PD) Deficient Erythrocytes. |
PUB Date Free Form |
c1983 |
Category Codes |
6T; 6A; 6E; 7D; 68A; 57Y; 57B; 57U; 99F |
NTIS Prices |
Not available NTIS |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
515818866 |
Origin |
NTIS |
Type |
CAT |