| Main Title |
Fas Signaling [electronic resource] / |
| Type |
EBOOK |
| Author |
Wajant, Harald.
|
| Publisher |
Springer US, |
| Year Published |
2006 |
| Call Number |
QR180-189.5 |
| ISBN |
9780387345734 |
| Subjects |
Medicine ;
Immunology ;
Oncology
|
| Internet Access |
|
| Collation |
VIII, 160 p. online resource. |
| Notes |
Due to license restrictions, this resource is available to EPA employees and authorized contractors only |
| Contents Notes |
FasL and Fas -- FasL-Independent Activation of Fas -- Role of Ceramide in CD95 Signaling -- Regulation of Fas Signaling by FLIP Proteins -- Fas-Induced Necrosis -- Fas-More Than an Apoptosis Inducer -- Retrograde Fas Ligand Signaling -- FasL and Fas in Liver Homeostasis and Hepatic Injuries -- Fas-Activation, Development and Homeostasis of T Cells -- The FasL-Fas System in Disease and Therapy -- Tools for Activation and Neutralization of Fas Signaling. Fas Signaling is focused on the signaling mechanisms and biology of the prototypic death receptor Fas, also called CD95 or APO-1. The chapters of this book cover, besides the well recognized apoptosis-related functions of Fas, its emerging role as a proinflammatory cytokine and as an inducer of alternative forms of cell death. Fas Signaling aims to provide the reader with an up-to-date survey of the various aspects of Fas biology and the open questions of the field are addressed. This title is intended for Ph.D and post-doctoral students starting to work in the field, but is also useful for everyone with an interest in the biology of this exciting molecule. |
| Place Published |
Boston, MA |
| Corporate Au Added Ent |
SpringerLink (Online service) |
| Title Ser Add Ent |
Medical Intelligence Unit |
| Host Item Entry |
Springer eBooks |
| PUB Date Free Form |
2006 |
| Series Title Untraced |
Medical Intelligence Unit |
| BIB Level |
m |
| Medium |
computer |
| Content |
text |
| Carrier |
online resource |
| Cataloging Source |
OCLC/T |
| OCLC Time Stamp |
20131218113537 |
| Language |
eng |
| Origin |
SPRINGER |
| Type |
EBOOK |
| OCLC Rec Leader |
02480nam a22004575i 45 |
