||Aspen Cancer Conference (8th): Molecular Mechanisms of Toxicity in Relation to the Genetics of Animal and Human Neoplasia. Held on July 17-22, 1993.
Tennant, R. W. ;
Prescott, D. M. ;
Puck, T. T. ;
Slaga, T. J. ;
Saffiotti, U. ;
||Health Effects Research Lab., Research Triangle Park, NC. Genetic Toxicology Div.
Malignant neoplasms ;
Occupational exposure ;
Genomic library ;
Species specificity ;
Cell death ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||Cancers arise as a consequence of the interactions between environmental factors and specific genes. The environmental factors range from the ubiquitous, such as sunlight, to the highly specific, such as occupational exposures to particular chemicals. The genes with which these factors interact include those that influence the metabolic fate and distribution of specific chemicals as well as those that may be targets for the action of chemicals. Since the magnitude and duration of exposure are critical factors in determining the consequences of chemical-gene interactions, the toxicological properties of environmental carcinogens are also significant determinants. The Eighth Aspen Cancer Conference, held on July 17, 22, 1993, assembled a diverse group of distinguished investigators whose interests and expertise encompass these issues. The topics were presented and discussed in eight sessions, the highlights of which are summarized herein. (Copyright (c) 1994 Wiley-Liss, Inc.)
||Pub. in Molecular Carinogenesis, v10 n3 p117-124 Jul 94.
||%AUT:G. N. /Wogan ;S. /Nesnow ;R. M. /McClain
|NTIS Title Notes
||Reprint: Aspen Cancer Conference (8th): Molecular Mechanisms of Toxicity in Relation to the Genetics of Animal and Human Neoplasia. Held on July 17-22, 1993.
||57Y; 57F; 57E
||PC A02/MF A01