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RECORD NUMBER: 9 OF 68

OLS Field Name OLS Field Data
Main Title Change in the DNA Content of the Nuclei of Tumor Cells in the Process of 'Progression' of the Induced Hepatoma (Izmenenie Soderzhaniya DNK v Yadrakh Opukholevykh Kletok v Protesse 'Progressii' Indutsirovannoi Hepatomy).
Author Pozharisskii, K. M. ; Shalumovich, V. N. ; Shaposhnikov., Ya. D. ;
CORP Author Environmental Protection Agency, Research Triangle Park, N.C. Translation Services Section.
Year Published 1973
Report Number EPA-TR-76-31;
Stock Number PB-259 072-T
Additional Subjects Neoplasms ; Deoxyribonucleic acids ; Cytochemistry ; Cells(Biology) ; Biochemistry ; Nucleic acids ; Liver ; USSR ; Translations ; Carcinogenesis
Holdings
Library Call Number Additional Info Location Last
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Status
NTIS  PB-259 072-T Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 16p
Abstract Biochemical and cytophotometric investigations have shown that the DNA content of tumors increased in comparison with the homologic normal tissues and that authors who have conducted investigations using cytophotometric methods have detected a direct correlation between the amount of DNA in the nuclei of tumor cells and the degree of the differentiation. Thus, with the increase in the duration of effect of a blastomogenic agent on animals, the relative amount of polyploid cells increases in the liver. At the same time, it was established that the DNA content of hepatic cells increases in the process of carcinogenesis in this organ. The indicated studies were devoted to an investigation of the DNA content in the nuclei of tumor cells or cells in the stage of malignization, and, therefore, the final stage of the investigation was the formed tumor.
Supplementary Notes Trans. of Voprosy Onkologii (USSR) v19 n3 p73-80 1973.(PC A02/MF A01)
Title Annotations +++Change in the DNA Content of the Nuclei of Tumor Cells in the Process of 'Progression' of the Induced Hepatoma (Izmenenie Soderzhaniya DNK v Yadrakh Opukholevykh Kletok v Protesse 'Progressii' Indutsirovannoi Hepatomy)--Translation.
PUB Date Free Form 1973
Category Codes 6A; 6E; 57F; 57O
NTIS Prices PC A02/MF A01
Document Type NT
Cataloging Source NTIS/MT
Control Number 323702873
Origin NTIS
Type CAT