||Letter from Eastman Kodak Company to US EPA regarding Information on 5-Methyl-2-Octanone 90-Day Feeding Study.
||Tennessee Eastman Co., Kingsport.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
||21 Feb 1979
Laboratory tests ;
Central nervous system ;
US EPA ;
In vivo analysis ;
Adverse effects ;
MHK solvent ;
Eastman Kodak Company
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||The submission reports that chronic administration of MHK Solvent (5-methyl-2-octanone; 72% minimum) to rats by gavage over a 90-day period induced signs of hind-limb weakness in several of the test animals. Histologic examination of peripheral and central nervous system sections revealed giant axonal neuropathy in the MHK Solvent-dosed rats.
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||57Y; 57S; 68G
||PC A02/MF A01