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RECORD NUMBER: 353 OF 1147

OLS Field Name OLS Field Data
Main Title Effect of Dibutylnitrosamine and Saccharin on Glutamyl Transpeptidase-Positive Foci and Liver Cancer.
Author Pereira, M. A. ; Herren, S. L. ; Britt, A. L. ;
CORP Author Health Effects Research Lab., Cincinnati, OH. ;Cincinnati Univ., OH. Coll. of Medicine.
Year Published 1983
Report Number EPA/600/J-83/236;
Stock Number PB84-245638
Additional Subjects Malignant neoplasms ; Antineoplastic agents ; Liver ; Reprints ; Nitrosamine/dibutyl ; Saccharin ; Cancer ; Foci
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB84-245638 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 8p
Abstract An attempt was made to evaluate whether the simultaneous administration of the urinary bladder tumor promoter, saccharin, and the substance being tested for carcinogenicity could be developed into a rapid and efficient bioassay for bladder carcinogens. Dibutylnitrosamine (DBN) a bladder and-to a lesser extent-liver carcinogen, was used as the test substance. The attempted evaluation failed because of the high incidence of liver cancer in the rats that simultaneously received DBN and saccharin.
Supplementary Notes Prepared in cooperation with Cincinnati Univ., OH. Coll. of Medicine.
Availability Notes Pub. in Environmental Health Perspectives, v50 p169-176 1983.
NTIS Title Notes Journal article.
Title Annotations Reprint: Effect of Dibutylnitrosamine and Saccharin on Glutamyl Transpeptidase-Positive Foci and Liver Cancer.
PUB Date Free Form c1983
Category Codes 6T; 6E; 57Y; 57O
NTIS Prices Not available NTIS
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 435627109
Origin NTIS
Type CAT