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RECORD NUMBER: 306 OF 1147

OLS Field Name OLS Field Data
Main Title Cytotoxicity of Halogenated Alkanes in Primary Cultures of Rat Hepatocytes from Normal, Partial Hepatectomized, and Preneoplastic/Neoplastic Liver.
Author Chang, L. W. ; Pereira, M. A. ; Klaunig, J. E. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;Medical Coll. of Ohio at Toledo.
Year Published 1985
Report Number EPA/600/J-85/219;
Stock Number PB86-121506
Additional Subjects Halogen organic compounds ; Toxicity ; Environmental surveys ; Bioassay ; Biochemistry ; Laboratory animals ; Risk ; Metabolism ; Rats ; Exposure ; Hazardous materials ; Cultures(Biology) ; Chloroform ; Liver neoplasms ; Reprints ; Toxic substances ; Environmental health ; Carcinogenesis ; Ethane/dibromo ; Ethane/dichloro ; Ethane/trichloro
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NTIS  PB86-121506 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/21/1988
Collation 12p
Abstract Six halogenated hydrocarbons: chloroform, 1,2-dibromoethane (1,2-DBE), 1,1-dichloroethane (1,1-DCE), 1,2-dichloroethane (1,2DCE), 1,1,1-trichloroethane (1,1,1-TCE) and 1,1,2-trichloroethane (1,1,2-TCE) were evaluated for their cytotoxicity in primary cultures of rat hepatocytes isolated from normal, partial hepatectomized and from preneoplastic/neoplastic rat liver. None of the six halogenated alkanes exhibited any difference in their cytotoxicity toward hepatocytes isolated from normal liver or from liver containing preneoplastic/neoplastic lesions induced by either procedure.
Supplementary Notes Pub. in Toxicology and Applied Pharmacology 80, p274-283 1985. Prepared in cooperation with Medical Coll. of Ohio at Toledo.
NTIS Title Notes Journal article.
Title Annotations Reprint: Cytotoxicity of Halogenated Alkanes in Primary Cultures of Rat Hepatocytes from Normal, Partial Hepatectomized, and Preneoplastic/Neoplastic Liver.
PUB Date Free Form c1985
Category Codes 6T; 6E; 57Y; 68G; 57U
NTIS Prices Not available NTIS
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 604416604
Origin NTIS
Type CAT