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OLS Field Name OLS Field Data
Main Title Alteration of Cellular Interactions in the Immune System: Natural Killer Activity and N Lymphocytes.
Author Burleson, G. R. ;
CORP Author Northrop Services, Inc., Research Triangle Park, NC.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1987
Report Number EPA-68-02-4450; EPA/600/D-87/302;
Stock Number PB88-106414
Additional Subjects Immunology ; Neoplasms ; Viral diseases ; Lymphocytes ; Killer cells(Natural) ; Immune system ; Suppressor cells ; NK(Natural killer)
Library Call Number Additional Info Location Last
NTIS  PB88-106414 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/21/1988
Collation 56p
Abstract N lymphocytes, like interferons, have three major biological functions: (1) antitumor activity; (2) antiviral activity; and (3) immunoregulatory activity. Antitumor activity is also referred to as natural killer (NK) activity which represents the non-MHC-restricted lysis of NK-sensitive tumor cells by effector cells obtained from a nonimmunized host. N lymphocytes play a pivotal role in a network of immune functions. The review discusses the (1) properties of natural killer activity, (2) importance of natural killer activity against tumor cells, (3) importance of N lymphocytes in viral infections, (4) regulation of natural killer activity by cytokines, (5) alteration of natural killer activity by suppressor cells, and (6) alteration of natural killer activity by chemicals.
Supplementary Notes Sponsored by Health Effects Research Lab., Research Triangle Park, NC.
PUB Date Free Form Sep 87
Category Codes 57J; 57E
NTIS Prices PC A04/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 735120872
Origin NTIS
Type CAT