| Main Title |
Characteristics of a Fish Colony of 'Poeciliopsis' and Its Use in Carcinogenicity Studies with 7,12-Dimethylbenz(a)anthracene and Diethylnitrosamine. |
| Author |
Schultz, R. J. ;
Schultz, M. E. ;
|
| CORP Author |
Connecticut Univ., Storrs. Biological Sciences Group.;Environmental Research Lab., Gulf Breeze, FL. |
| Year Published |
1984 |
| Report Number |
EPA/600/J-84/268; |
| Stock Number |
PB85-193076 |
| Additional Subjects |
Fishes ;
Genetics ;
Carcinogens ;
Toxicity ;
Laboratory animals ;
Aromatic polycyclic hydrocarbons ;
Nitroso compounds ;
Amines ;
Females ;
Liver ;
Neoplasms ;
Tissues(Biology) ;
Hybridization ;
Exposure ;
Mexico ;
Reprints ;
Benzathracene/dimethyl ;
Nitrosamine/diethyl ;
Poeciliopsis ;
Clones
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB85-193076 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
11p |
| Abstract |
The viviparous fish Poecilliopsis from northwestern Mexico is characterized according to its potential in cancer research. A colony of these fishes started in 1961 includes inbred strains of P. lucida (M61-9, M61-31, M61-35, and S68-4), P. monacha (S68-4 and S68-5), and P. viriosa (M65-23), which have been demonstrated by electrophoresis and tissue graft analysis to be homozygous. All-female species of hybrid origin are represented by 12 clones which, although highly heterozygous, are genetically identical isogenic and readily accept within-clone tissue transplants. Two studies are cited in which hepatic tumors were chemically induced. Hepatic tumors, initially induced with DENA have been successfully transplanted into the muscle tissue and abdominal cavity of members of the same strain. |
| Availability Notes |
Pub. in National Cancer Institute Monograph 65, p5-13 May 84. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Characteristics of a Fish Colony of 'Poeciliopsis' and Its Use in Carcinogenicity Studies with 7,12-Dimethylbenz(a)anthracene and Diethylnitrosamine. |
| PUB Date Free Form |
c1984 |
| Category Codes |
6E; 6C; 6T; 14B; 57E; 57Z; 57Y |
| NTIS Prices |
Not available NTIS |
| Primary Description |
600/04 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
519921737 |
| Origin |
NTIS |
| Type |
CAT |
