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OLS Field Name OLS Field Data
Main Title Ames Salmonella/mammalian Microsome Mutagenicity Test and Reverse Mutation Assay - E. Coli Wp2 Uvra a (Standard Plate Test and Preincubation Test) (Oct. 19, 1988) W-letter 12/16/1991.
CORP Author BASF A.G., Limburgerhof (Germany, F.R.). Agricultural Research Station.; BASF Corp., Mount Olive, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1991
Report Number 86-920000590
Stock Number OTS0535474
Additional Subjects Toxicology ; Health effects ; 4-methylbenzaldehyde (104-87-0) ; Genotoxicity ; Gene Mutations ; Bacteria ; In Vitro ; Toxic substances ; Laboratory animals ; CAS No 104-87-0
Library Call Number Additional Info Location Last
NTIS  OTS0535474 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 03/10/2010
Collation 32p
Abstract P-Tolualdehyde (CAS No. 104-87-0) was evaluated for mutagenicity in the Ames test (strains TA1535, TA100, TA1537, TA98) with and without metabolic activation (S-9 mix) and in the Escherichia coli (WP2 uvrA) reverse mutation assay at a dose range of 20 ug - 5000 ug/plate in the standard plate test (SPT) and 4 ug - 2500 ug/plate in the preincubation test (PIT). No bacteriotoxic effect was observed with E. coli. Bacteriotoxicity was detected in all Salmonella strains detected at 2500 ug/plate (PIT) and at 5000 ug/plate (SPT). The test substance was determined to be non- mutagenetic.
Supplementary Notes The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with BASF Corp., Mount Olive, NJ.
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PUB Date Free Form 1991
Category Codes 57Y; 57U; 68G; 99; 44G
NTIS Prices PC A04/MF A04
Document Type NT
Cataloging Source NTIS/MT
Control Number 028803390
Origin NTIS
Type CAT