| Main Title |
Mutagenicity Evaluation of C-56 (crotonaldehyde) in the Ames Salmonella/microsome Plate Test (final Report) with Cover Letter Dated 03/11/1987. |
| CORP Author |
Litton Bionetics, Inc., Bethesda, MD.; Occidental Chemical Corp., Grand Island, NY.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1987 |
| Report Number |
86870000237 |
| Stock Number |
OTS0513187 |
| Additional Subjects |
Toxicology ;
Health effects ;
Crotonaldehyde (2-butenal) (4170-30-3) ;
Genotoxicity ;
Gene Mutations ;
Bacteria ;
In Vitro ;
Toxic substances ;
Laboratory animals ;
CAS No 4170-30-3
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0513187 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
14p |
| Abstract |
The mutagenicity of crotonaldehyde was evaluated in Salmonella tester strains TA1535, TA1537, TA1538, TA98 and TA100, both in the presence and absence of added metabolic activation by Aroclor-induced rat liver S9 fraction. Based on preliminary bacterial toxicity determinations, crotonaldehyde was tested for mutagenicity at concentrations of 0.005, 0.01, 0.10, 1.0, 5.0 and 10.0 ul/plate using the agar incorporation method. Crotonaldehyde did not produce a positive response in any bacterial tester strain, either with or without metabolic activation. The investigators reported crotonaldehyde was toxic to all bacterial strains at concentrations of 1, 5 and 10 ul/plate. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with Occidental Chemical Corp., Grand Island, NY. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
1987 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A03/MF A03 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028801740 |
| Origin |
NTIS |
| Type |
CAT |
