||Behavioral Evaluation of the Irritating Properties of Ozone.
Tepper, J. S. ;
Wood, R. W. ;
||Rochester Univ., NY. School of Medicine and Dentistry.;Health Effects Research Lab., Research Triangle Park, NC.
Air pollution ;
Behavior disorders ;
Laboratory animals ;
Hazardous materials ;
Air pollution effects(Human) ;
Air pollution effects(Animals) ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||The sensory irritant properties of ozone have been considered to be responsible for symptoms that occur in humans after exposure. This assumption has not been studied explicitly. One way to assess the aversive properties of airborne irritants is to give the exposed individual an opportunity to control the duration of exposure, i.e., escape from the irritant. Mice were trained to turn off 100-ppm ammonia, a concentration that, in humans, is irritating to the upper airways. After the determination of ammonia concentration-effect curves, ozone was substituted for ammonia. Additional mice with no history of ammonia termination were trained to terminate ozone exposure, indicating that the aversive properties of ozone were not dependent on previous experience with other airborne irritants.
||Pub. in Toxicology and Applied Pharmacology 78, n3 p404-411 May 85.
|NTIS Title Notes
||Reprint: Behavioral Evaluation of the Irritating Properties of Ozone.
|PUB Date Free Form
||6T; 6E; 5J; 68G; 57Y; 57U; 57S
||Not available NTIS