Main Title |
Behavioral Toxicity of Trihalomethane Contaminants of Drinking Water in Mice. |
Author |
Balster, Robert L. ;
Borzelleca, Joseph F. ;
|
CORP Author |
Medical Coll. of Virginia, Richmond. Dept. of Pharmacology.;Health Effects Research Lab., Research Triangle Park, NC. |
Year Published |
1982 |
Report Number |
EPA-R-804701; EPA-600/J-81-370; |
Stock Number |
PB83-187880 |
Additional Subjects |
Toxicology ;
Trihalomethane ;
Potable water ;
Bioassay ;
Dosage ;
Mice ;
Laboratory animals ;
Reprints ;
Drinking water ;
Water pollution effects(Animals)
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB83-187880 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
12p |
Abstract |
The behavioral toxicity of trichloromethane (TCM), dichlorobromomethane (DCBM), dibromochloromethane (DBCM) and tribromonethane (TBM) was evaluated following oral administration in mice. A variety of dosage regimens and behavioral measures were used. Studies included acute dose effect, 14- and 90-day treatments at 300 and 3000 times the estimated average human daily intake of contaminated drinking water, 30 days of 100 mg/kg/day, and 60 days of 100 and 400 mg/kg/day. In addition, TCM was tested for the production of taste aversions with 10-day administration and for behavioral teratology in offspring following extensive perinatal exposure. |
Supplementary Notes |
Pub. in Environmental Health Perspectives, v46 p127-136 1982. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Behavioral Toxicity of Trihalomethane Contaminants of Drinking Water in Mice. |
PUB Date Free Form |
1982 |
Category Codes |
6T; 6F; 57Y; 68D |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
320321861 |
Origin |
NTIS |
Type |
CAT |