||Automotive Exhaust and Mouse Activity: Relationships between Pollutant Concentrations and Decreases in Wheel Running.
Gage, Michael I. ;
||Health Effects Research Lab., Research Triangle Park, NC.
Carbon monoxide ;
Exhaust gases ;
Radiation effects ;
Laboratory animals ;
Automobile exhaust ;
Air pollution effects(Animals) ;
Toxic substances ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||Groups of male and female mice inhaled either clean air, 100 ppm carbon monoxide, or light-irradiated and nonirridiated automotive exhaust containing nominally 25, 50, 75, or 100 ppm carbon monoxide in three tests with exposure lasting from 4 to 7 days. Exhaust from a factory or lean-tuned engine in the first and third tests reversibly suppressed activity wheel running during exposure in mice of both sexes by as much as 78.3 and 83.1 percent respectively. Light-irradiated exhaust suppressed running more than nonirradiated exhaust. For the second test, when the engine was tuned to be low in pollutants other than carbon monoxide, exhaust did not suppress running. Exposure to carbon monoxide alone only slightly decreased running in male mice, but increased running in female mice.
||Pub. in Archives of Environmental Health v34, n3, p164-168 1979. Also pub. as ISSN-0003-9896.
|NTIS Title Notes
||Reprint: Automotive Exhaust and Mouse Activity: Relationships between Pollutant Concentrations and Decreases in Wheel Running,
|PUB Date Free Form
||6T; 6F; 6R; 57Y; 57V; 68A
||PC A02/MF A01