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OLS Field Name OLS Field Data
Main Title Evaluation of mutagenic effects of diesel emissions : I. tests for heritable and germ-cell effects in the mouse /
Author Russell, L. B. ; Generoso, W. M. ; Russell, W. L. ; Oakberg, E. F.
Other Authors
Author Title of a Work
Generoso, W. M.
Russell, W. L.
Oakberg, E. F.
CORP Author Oak Ridge National Lab., TN.;Health Effects Research Lab., Research Triangle Park, NC.
Publisher U.S. Environmental Protection Agency, Health Effects Research Laboratory,
Year Published 1981
Report Number PB81-235814; EPA-600/1-81-056; EPA-79-DX-0710
Stock Number PB81-235814
OCLC Number 758900825
Subjects Diesel motor exhaust gas--Physiological effect. ; Mutagenicity testing.
Additional Subjects Exhaust emissions ; Mutagens ; Toxicology ; Evaluation ; Mice ; Bioassay ; Exposure ; Laboratory animals ; Respiration ; Air pollution ; Mutagenesis ; Diesel engine exhaust ; Air pollution effects(Animals)
Internet Access
Description Access URL
http://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=9100XVOE.PDF
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
ELCD  EPA 600-1-81-056 NVFEL Library/Ann Arbor, MI 10/31/2011 STATUS
NTIS  PB81-235814 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation vii, 26 p. : charts ; 28 cm.
Abstract The Environmental Protection Agency, under the Clean Air Act, is charged with the responsibility for regulating the emissions from new motor vehicles. In order to assess potential heritable effects of diesel exhaust, mice were exposed to whole diesel exhaust by inhalation and a number of genetic end points were studied. Exposure times varied from 5 to 10 weeks for the different groups. The diesel particulate concentration averaged 6 mg/cu. m. during the exposure period of 8 hours per day and 7 days of the week. The results of all genetic assays in both sexes were negative; however, small but unequivocal effects on the reproductive performance of females of one strain were observed.
Notes Includes bibliographical references. "PB81-235814." "Aug 81"--Cover. "EPA-600/1-81-056"--T.p. "Contract No. EPA-D-X0710"--T.p. "EPA Project Manager and Technical Project Officer: Larry Claxton"--T.p. "EPA Technical Project Officers for Exposure: John Orthoefer and Michael Pereira"--T.p. "ORNL Project Manager and Technical Project Officer: Laine B. Russell"--T.p. "This study was conducted in cooperation with the Department of Energy at the Oak Ridge National Laboratory interagency agreement DOE No. 40-728-78"--T.p.
Contents Notes The Environmental Protection Agency, under the Clean Air Act, is charged with the responsibility for regulating the emissions from new motor vehicles. In order to assess potential heritable effects of diesel exhaust, mice were exposed to whole diesel exhaust by inhalation and a number of genetic end points were studied. Exposure times varied from 5 to 10 weeks for the different groups. The diesel particulate concentration averaged 6 mg/m3 during the exposure period of 8 hours per day and 7 days of the week. The results of all genetic assays in both sexes were negative; however, small but unequivocal effects on the reproductive performance of females of one strain were observed.
Place Published Research Triangle Park, NC
Corporate Au Added Ent Oak Ridge National Laboratory. Biology Division.; United States. Environmental Protection Agency. Office of Research and Development. Health Effects Research Laboratory (Research Triangle Park, N.C.)
NTIS Title Notes Final rept..
PUB Date Free Form Aug 81
Category Codes 6T; 6E; 57Y; 57E
NTIS Prices PC A03/MF A01
Primary Description 600/11
BIB Level m
Cataloging Source OCLC/T
Control Number 323802630
OCLC Time Stamp 20111027161344
Language eng
Origin OCLC
Type MERGE
OCLC Rec Leader 02519nam 2200409Ka 45020