Main Title |
Some Effects of the Formamidine Pesticide Chlordimeform on the Behavior of Mice. |
Author |
Landauer, M. R. ;
Tomlinson, W. T. ;
Balster, R. L. ;
MacPhail, R. C. ;
|
CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
Year Published |
1984 |
Report Number |
EPA/600/J-84/210; |
Stock Number |
PB85-161347 |
Additional Subjects |
Pesticides ;
Toxicology ;
Behavior ;
Physiological effects ;
Mice ;
Laboratory animals ;
Reprints ;
Chlordimeform ;
Neurotoxicity
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB85-161347 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
11p |
Abstract |
Three experiments were performed to determine the behavioral effects of acutely administered chlordimeform (1-56 mg/kg, i.p.) to male mice. In Experiment I, dosages of 30 and 56 mg/kg decreased the amount of time spent investigating a female conspecific. In Experiment II, large dosages of chlordimeform (30 and 56 mg/kg) decreased vertically directed activity (rearing) to a proportionately greater extent than horizontally directed activity (ambulation). In Experiment III, chlordimeform produced conditioned flavor aversions that were intermediate at 10 mg/kg and maximal at 30 mg/kg. In an additional experiment (Experiment IV), the LD50 for chlordimeform was determined to be 95.6 mg/kg. Behavioral effects were thus obtained at dosages that were approximately 10 to 30% of the LD50. |
Availability Notes |
Pub. in NeuroToxicology 5, n2 p91-100 1984. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Some Effects of the Formamidine Pesticide Chlordimeform on the Behavior of Mice. |
PUB Date Free Form |
c1984 |
Category Codes |
6T; 57Y; 68E |
NTIS Prices |
Not available NTIS |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
511622362 |
Origin |
NTIS |
Type |
CAT |