| Main Title |
Support: Letter from (Confidential) to USEPA reporting Results of an Approximate Lethal Dose Study in Mice with (Confidential), a Substituted Benzoheterocycle, dated 11/03/1993. (Sanitized). |
| CORP Author |
; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1993 |
| Report Number |
8EHQ-1193-9022S |
| Stock Number |
OTS0538519-1 |
| Additional Subjects |
Toxicology ;
Health effects ;
Toxic substances ;
Substituted benzoheterocycle ;
Mice ;
Gavage
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0538519-1 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
6p |
| Abstract |
On April 12, 1993, we reported the results of an approximate lethal dose study in mice with this compound. This letter is to inform you of the results of a preliminary pharmacokinetic screen in rats. The test material was administered once by gavage to male rats at a dose level of 25 mg/kg. All rats survived. However, at 24 and 48 hours post dose, several rats exhibited clinical signs suggestive of central nervous system involvement, including splayed limbs, imbalance, abnormal gait and impaired locomotion. No formal report will be written for this study. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
4 Nov 1993 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A02/MF A02 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
018801120 |
| Origin |
NTIS |
| Type |
CAT |
