| Main Title |
Initial Submission: Letter from (Confidential Source) to USEPA re: In-Life Portion of a Two-Generation Reproduction Inhalation Study with Normal Propyl Bromide in Rats, dated 08/10/1999. (Sanitized). |
| CORP Author |
; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1999 |
| Report Number |
8EHQ-0899-14528S |
| Stock Number |
OTS0559775 |
| Additional Subjects |
Toxicology ;
Inhalation ;
Bromides ;
Rats ;
Fertility ;
Reproduction(Biology) ;
Solvents ;
Laboratory animals ;
Females ;
Methodology ;
Exposure ;
Weight ;
Normal propyl bromide ;
Sprague Dawley rats ;
CAS No 106-94-5
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0559775 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
10p |
| Abstract |
The in-life portion of a two generation reproduction inhalation study using Normal Propyl Bromide in Sprague Dawley rats, sponsored by the Brominated Solvents Committee, was initiated at Huntingdon Life Sciences laboratories, East Millstone, New Jersey, in April, 1999. The study was terminated July 5, 1999, when the first generation control animal group (which was not exposed to the test chemical) failed to produce the 20 litters of offspring required for a valid study the the methodology used. Reasons for the low fertility in this group are not known. Similar numbers of litters were seen in all but the highest exposure group, which failed to produce offspring. Other effects seen in the treatment groups were decreased weight gains in the two highest groups of females over the majority of the study. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
11 Aug 1999 |
| Category Codes |
57Y; 57O; 68G |
| NTIS Prices |
PC A02/MF A02 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
010500840 |
| Origin |
NTIS |
| Type |
CAT |
