Full Record Display for the EPA National Library Catalog

RECORD NUMBER: 42 OF 281

OLS Field Name OLS Field Data
Main Title Catabolism of Aromatic Biogenic Amines by 'Pseudomonas aeruginosa' PA01 via meta Cleavage of Homoprotocatechuic Acid (Journal Version).
Author Cuskey, S. M. ; Olsen, R. H. ;
CORP Author Environmental Research Lab., Gulf Breeze, FL. ;Michigan Univ., Ann Arbor. Medical School.
Publisher c1988
Year Published 1988
Report Number EPA/600/J-88/109;
Stock Number PB89-120067
Additional Subjects Biogenic amines ; Pseudomonas aruginosa ; Metabolism ; Bacteria ; Tyramine ; Oxygenases ; NADH ; NADPH oxidoreductases ; Analklyamines ; Mutations ; Enzyme induction ; Molecular cloning ; Chromosome mapping ; Reprints ; Octopamine ; Benzene methanol/(aminomethyl)-hydroxy
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB89-120067 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 03/14/1989
Collation 8p
Abstract Pseudomonas aruginosa PA01 catabolized the aromatic amines tyramine and octopamine through 4-hydroxyphenylacetic acid and 3,4-dihydroxyphenylacetic acid (HPA). Meta ring cleavage was mediated by 3-4-dihydroxyphenylacetate 2,3-dioxygenase (HPADO), producing 2-hydroxy-5-carboxymethylmuconic semialdehyde (MSA). An NAD-dependent dehydrogenase caused the disappearance of the yellow MSA product, probably forming 2-hydroxy-5-carboxymethylmuconic acid. Induction studies with extracts from mutant cells indicated that the inducer of HPADO was HPA and/or MSA. Strains PA01.221 (tynCl) and PA01.303 (tynDI) have chromosomal mutations causing a deficiency in the activity necessary for conversion of 4-hydroxyphenylacetic acid to HPA. (Copyright (c) 1988 American Society for Microbiology.)
Supplementary Notes Prepared in cooperation with Michigan Univ., Ann Arbor. Medical School.
Availability Notes Pub. in Jnl. of Bacteriology, v170 n1 p393-399 Jan 88.
NTIS Title Notes Journal article.
Title Annotations Reprint: Catabolism of Aromatic Biogenic Amines by 'Pseudomonas aeruginosa' PA01 via meta Cleavage of Homoprotocatechuic Acid (Journal Version).
Category Codes 57K; 57B; 57F
NTIS Prices Not available NTIS
Primary Description 600/04
Document Type NT
Cataloging Source NTIS/MT
Control Number 901217419
Origin NTIS
Type CAT