Main Title |
Developmental Change in Reversal Learning of an Olfactory Discrimination. |
Author |
Saperstein, L. A. ;
Kucharski, D. ;
Stanton, M. E. ;
|
CORP Author |
Duke Univ., Durham, NC. ;Ohio Univ., Athens.;Health Effects Research Lab., Research Triangle Park, NC. |
Publisher |
c1989 |
Year Published |
1989 |
Report Number |
EPA/600/J-89/459; |
Stock Number |
PB91-109512 |
Additional Subjects |
Conditioning(Learning) ;
Smell ;
Olfactory organs ;
Rats ;
Hippocampus ;
Odors ;
Memory ;
Reprints ;
Avoidance learning ;
Ontogeny ;
Nasal septum
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB91-109512 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
9p |
Abstract |
Three experiments examined developmental changes in the reversal of a learned discrimination in an olfactory conditioning paradigm. Preweanling rats were exposed to an odor (CS+) paired with footshock, and a different odor (CS-) that was explicitly unpaired with footshock. They were then immediately tested for their preference between the CS+ and CS- odors. In Experiment 1, animals trained at 12- or 18-days of age showed equivalent conditioned aversions to the CS+. When the significance of the cues was reversed the younger animals showed rapid reversal learning, i.e. their aversion to the original CS+ was displaced by an aversion to the original CS-. But the 18-day-old animals were slower to acquire reversal of the discrimination. Experiment 2 showed a similar pattern of results when animals received separate preference tests involving the CS+ vs a novel odor, or the CS- vs a novel odor. In Experiment 3, intact 18-day-old rats and 18-day-olds with damage to the septum and fornix showed equivalent conditioned aversions to the CS+. |
Supplementary Notes |
Pub. in Phychobiology, v17 n3 p293-299 1989. Prepared in cooperation with Ohio Univ., Athens. Sponsored by Health Effects Research Lab., Research Triangle Park, NC. |
Title Annotations |
Reprint: Developmental Change in Reversal Learning of an Olfactory Discrimination. |
Category Codes |
57S; 57T |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/10 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
034834564 |
Origin |
NTIS |
Type |
CAT |