| Main Title |
Evaluation of the Three-hour Lc50 of Aerosolized Benzotriazole (Final Report) with Attachments and Cover Letter Dated 06/12/1989. |
| CORP Author |
Huntingdon Research Center, Inc., Baltimore, MD.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1989 |
| Report Number |
86-890000598 |
| Stock Number |
OTS0520637 |
| Additional Subjects |
Toxicology ;
Health effects ;
Benzotriazole (95-14-7) ;
Acute Toxicity ;
Mammals ;
Rats ;
Inhalation ;
Toxic substances ;
Laboratory animals ;
CAS No 95-14-7
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0520637 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
16p |
| Abstract |
Acute inhalation toxicity was evaluated in 5 groups of 10 male Sprague-Dawley rats receiving a single application of benzotriazole at concentration levels of 0.78, 1.46, 2.03, 2.23, and 2.71 mg/L for 3 hours. Mortality was observed at all concentration levels. The LC50 was 1.91 mg/L (95% confidence limits = 1.59 to 2.29 mg/L). Clinical observations included deep abdominal breathing with open mouth gasping. Gross necropsy revealed a severe accumulation of white frothy fluid in the trachea and a moderate to severe incidence of dark red hemorrhagic areas in the lungs. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
1989 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A03/MF A03 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028802070 |
| Origin |
NTIS |
| Type |
CAT |
