| Main Title |
US EPA Submission Summary Report: Carbamic Acid Nitrile (Sanitized). |
| CORP Author |
; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
2000 |
| Report Number |
8EHQ-0490-0952S |
| Stock Number |
OTS0524054-3 |
| Additional Subjects |
Toxicology ;
Health effects ;
Carbamic Acid Nitrile ;
Chronic Toxicity ;
Carcinogenicity ;
Mammals ;
Mice ;
Oral ;
Diet ;
Toxic substances ;
Laboratory animals ;
CAS No 420-04-2
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0524054-3 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
5p |
| Abstract |
Cyanamide (CAS No. 420-04-2) was evaluated for carcinogenicity. The test substance was administered in the drinking water of male and female Crl:CD-1(ICR)-BR mice (60/sex/group) at dose levels of 0, 70, 200, or 600 ppm for 100 weeks (males) and 104 weeks (females). Preliminary findings reported 8 cases of benign granulosa-theca tumors of the ovary in females at the 600 ppm dose level. In the control group, 2 similar tumors were also found. Pathological findings indicated five instances of ovarian hyperplastic lesions. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
2000 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A01/MF A01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028802530 |
| Origin |
NTIS |
| Type |
CAT |
