Main Title |
Acute Vapor Inhalation Study in Fischer 344 Rats Using Aerothene Tt with Cover Letter Dated 03/22/1988. |
CORP Author |
Dow Chemical Co., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
Year Published |
1988 |
Report Number |
86-880000173 |
Stock Number |
OTS0514062 |
Additional Subjects |
Toxicology ;
Health effects ;
1 ;
1 ;
1-trichloroethane (71-55-6) ;
Acute Toxicity ;
Mammals ;
Rats ;
Inhalation ;
Toxic substances ;
Laboratory animals ;
CAS No 71-55-6
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
OTS0514062 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
34p |
Abstract |
Acute inhalation toxicity was evaluated in groups of 5 male and 5 female Fischer 344 rats exposed to Aerothene TT (1,1,1-trichloroethane) at actual concentrations of 15,523, 18,425, or 21,063 ppm for 4 hours. Mortality was observed in 3 females in the 18,425 ppm dose group and all animals in the highest dose group. The LC50 value was reported to be between 18,425 - 21,063 ppm for males and calculated to be 18,000 ppm (16,600-19,400 ppm 95% confidence limits) for females by the moving average method. Clinical observations included lethargy and unresponsiveness. Gross necropsy revealed clear facial soiling and visceral congestion. |
Supplementary Notes |
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Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
PUB Date Free Form |
1988 |
Category Codes |
57Y; 57U; 68G; 99; 44G |
NTIS Prices |
PC A04/MF A04 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
028801890 |
Origin |
NTIS |
Type |
CAT |