Main Title |
Inhalation Approximate Lethal Concentration of Formamide (Sanitized). |
CORP Author |
Du Pont de Nemours (E.I.) and Co., Newark, DE. Haskell Lab. for Toxicology and Industrial Medicine.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
Year Published |
2000 |
Report Number |
86-880000120S |
Stock Number |
OTS0514010 |
Additional Subjects |
Toxicology ;
Health effects ;
Formamdie (75-12-7) ;
Acute Toxicity ;
Mammals ;
Rats ;
Inhalation ;
Toxic substances ;
Laboratory animals ;
CAS No 75-12-7
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
OTS0514010 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
10p |
Abstract |
Acute inhalation toxicity was evaluated in groups of 6 male Crl:CDBR rats exposed to formamide at mean analytical concentrations of 1.3, 2.0, 5.1, 14, 19 or 21 mg/L for 4 hours. The test atmosphere was generated by metering the test material into a round-bottom flask heated to 100-210 deg C for concentrations less than 19 mg/L. The two highest atmospheric concentrations were generated with a nebulizer. Mortality was observed in 1 animal in the 21 mg/L dose group; the ALC was reported to be 21 mg/L. Clinical observations included lethargy, hunched posture, ocular and nasal discharges, partially-closed eyes, diarrhea, brown-stained perineum, and weight loss. Gross necropsy was not reported. |
Supplementary Notes |
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Availability Notes |
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PUB Date Free Form |
2000 |
Category Codes |
57Y; 57U; 68G; 99; 44G |
NTIS Prices |
PC A02/MF A02 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
028801870 |
Origin |
NTIS |
Type |
CAT |