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RECORD NUMBER: 514 OF 2096

Main Title Inhalation Approximate Lethal Concentration of Formamide (Sanitized).
CORP Author Du Pont de Nemours (E.I.) and Co., Newark, DE. Haskell Lab. for Toxicology and Industrial Medicine.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 2000
Report Number 86-880000120S
Stock Number OTS0514010
Additional Subjects Toxicology ; Health effects ; Formamdie (75-12-7) ; Acute Toxicity ; Mammals ; Rats ; Inhalation ; Toxic substances ; Laboratory animals ; CAS No 75-12-7
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NTIS  OTS0514010 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 10p
Abstract Acute inhalation toxicity was evaluated in groups of 6 male Crl:CDBR rats exposed to formamide at mean analytical concentrations of 1.3, 2.0, 5.1, 14, 19 or 21 mg/L for 4 hours. The test atmosphere was generated by metering the test material into a round-bottom flask heated to 100-210 deg C for concentrations less than 19 mg/L. The two highest atmospheric concentrations were generated with a nebulizer. Mortality was observed in 1 animal in the 21 mg/L dose group; the ALC was reported to be 21 mg/L. Clinical observations included lethargy, hunched posture, ocular and nasal discharges, partially-closed eyes, diarrhea, brown-stained perineum, and weight loss. Gross necropsy was not reported.
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PUB Date Free Form 2000
Category Codes 57Y; 57U; 68G; 99; 44G
NTIS Prices PC A02/MF A02
Document Type NT
Cataloging Source NTIS/MT
Control Number 028801870
Origin NTIS
Type CAT