||Initial Submission: Chronic Dietary Administration of Maleic Anhydride with Cover Letter dated 09/08/1992.
||ITT Research Inst., Lanham, MD.; Union Carbide Corp., Danbury, CT.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Health effects ;
Toxic substances ;
Maleic anhydride ;
Chronic toxicity ;
CAS No 108-31-6
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||Maleic anhydride was evaluated for toxicologic and/or carcinogenic effects in male and female Fischer 344 rats following dietary administration at levels of 100, 32, and 10 ag/kg/day. A control group received only the basal diet (Wayne Laboratory Meal). The criteria evaluated for compound related effects included: mortality, gross and behavioral signs of toxic or pharmacologic effects, body weights, food and compound consumption, clinical laboratory analysis (hematology, biochemistry, urinalyses), ophthalmology, neurological signs, organ weights and organ/100 g body weight, and gross and microscopic pathology.
||The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
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|PUB Date Free Form
||8 Sep 1992
||57Y; 57U; 68G; 99; 44G
||PC A03/MF A03