Main Title |
Multicompartment Kinetic Models for Lead. 2. Linear Kinetics and Variable Absorption in Humans without Excessive Lead Exposures. |
Author |
Marcus, A. H. ;
|
CORP Author |
Washington State Univ., Pullman. Dept. of Pure and Applied Mathematics.;Health Effects Research Lab., Research Triangle Park, NC. |
Year Published |
1985 |
Report Number |
EPA/600/J-85/425; |
Stock Number |
PB86-220381 |
Additional Subjects |
Lead(Metal) ;
Toxicology ;
Metabolism ;
Diet ;
Models ;
Reprints ;
Multicompartment models
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB86-220381 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
16p |
Abstract |
Multicompartment models with constant fractional transfer rates have been fitted to experimental data on lead metabolism in four subjects studied by M. B. Rabinowitz, G. W. Wetherill, and J. D. Kopple (Science 182, 725-727, 1973; Environ. Health Perspect. 7, 145-153, 1974; Arch. Environ. Health 31, 220-223, 1976; J. Clin. Invest. 58, 260-270, 1976; J. Lab Clin. Med. 90, 238-248, 1977). Long-term retention is estimated for blood, soft tissue, cortical and trabecular bone pools, and for facial hair. The absorption of lead from diet is shown to change with time, but no evidence was found for other variable or nonlinear kinetic mechanisms of lead metabolism in humans without excessive lead exposure. |
Supplementary Notes |
Pub. in Environmental Research 36, p459-472 1985. Sponsored by Health Effects Research Lab., Research Triangle Park, NC. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Multicompartment Kinetic Models for Lead. 2. Linear Kinetics and Variable Absorption in Humans without Excessive Lead Exposures. |
PUB Date Free Form |
c1985 |
Category Codes |
6T; 6P; 57Y; 57S |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
625518777 |
Origin |
NTIS |
Type |
CAT |