Main Title |
Teratogenic Effects of Cadmium in Rats. |
Author |
Chernoff., Neil ;
|
CORP Author |
Environmental Protection Agency, Perrine, Fla. Primate and Pesticides Effects Lab. |
Year Published |
1973 |
Stock Number |
PB-277 619 |
Additional Subjects |
Cadmium ;
Congenital abnormalities ;
Toxicology ;
Parenteral infusions ;
Rats ;
Experimental data ;
Laboratory animals ;
Dosage ;
Mortality ;
Lung ;
Reprints ;
Teratogenesis ;
Teratology ;
Fetus ;
Toxic substances
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB-277 619 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
4p |
Abstract |
The teratogenic effects of subcutaneous injections of cadmium in CD rats were investigated. Injections of 4-12 mg/kg CdCl2 on 4 consecutive days beginning on days 13-16 of gestation resulted in a dose-related rise in the fetal death rate, decrease in fetal weight, and increase in the rate of anomalies. The anomalies included micrognathia, cleft palate, clubfoot, and small lungs. The lung/body weight ratios were significantly reduced in fetuses of animals injected with 8 mg/kg CdCl2 on days 14-17 of gestation. The data indicate that this was a specific retardation and not merely a reflection of differential organ growth rates and overall fetal growth retardation. |
Supplementary Notes |
Pub. in Teratology, v8 n1 p29-32, Aug 73. |
Availability Notes |
Included in the report, Journal Articles on Toxicology. Group 1, PB-277 586. |
Title Annotations |
Reprint: Teratogenic Effects of Cadmium in Rats, |
PUB Date Free Form |
26 Mar 73 |
Category Codes |
6T; 57Y |
NTIS Prices |
(Order as PB-277 586, MF A01) |
Primary Description |
500/01 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
323734562 |
Origin |
NTIS |
Type |
CAT |