| Main Title |
Acute Oral Toxicity Study with RD-2 (X182/2463) in Male Albino Rats with Cover Letter. |
| CORP Author |
Industrial Bio-Test Labs., Inc., Northbrook, IL.; CIBA-GEIGY Corp., Greensboro, NC.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1983 |
| Report Number |
878213971 |
| Stock Number |
OTS-0206476 |
| Additional Subjects |
Toxicity ;
Laboratory animals ;
Rats ;
Hazardous materials ;
Toxic substances ;
Dose levels ;
Ingestion ;
Oral doses ;
Glycidol ;
Oxirane 22-14-butanediylbis ;
Oxymethylene-bis ;
CAS No 2425-79-8
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0206476 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
939p |
| Abstract |
Young albino rats derived from Sprague-Dawley stock were used as test animals. All animals were kept under observation for 5 days prior to experimental use, during which period they were checked for general health and suitability as test animals . The animals were housed in stock cages and were permitted a standard laboratory diet plus water ad libitum, except during the 16-hour period immediately prior to oral intubation when food was withheld. A range of several dose levels was studied using 1 rat per level. All doses were administered directly into the stomach of the rats using a hypodermic syringe equipped with a ball-tipped intubating needle. After oral administration of the test material, the rats were housed individually in suspended, wire-mesh cages and observed for the following 14 days. Initial and final body weights, mortalities and reactions were recorded. A necropsy examination was conducted on all animals. At the end of the observation period, the approximate acute oral lethal dose of the test material was determined. The test material was then assigned a classification. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
31 Jan 1983 |
| Category Codes |
57Y |
| NTIS Prices |
PC A99/MF E08 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
019000170 |
| Origin |
NTIS |
| Type |
CAT |
