||Studies on the Percutaneous Absorption of Parathion and Paraoxon, III. Rate of Absorption of Parathion.
Fredriksson., Torsten ;
||Communicable Disease Center, Atlanta, Ga.
||PB-280 570; PB-280 565
Laboratory animals ;
In vivo analysis ;
Experimental data ;
Labeled substances ;
Cholinesterase inhibitors ;
Phosphorus organic compounds ;
Phosphoric acid/(diethyl-ester)-(nitrophenyl-ester) ;
Environmental health ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||The rate of percutaneous absorption of parathion has been estimated in vivo by following the disappearance from a topical deposit of 32P-labelled material in the cat. There was a definite tendency towards inhibition of plasma cholinesterase activity in two cats, while a third animal failed to show this. The amount of radioactivity in the blood five hours after the application corresponded to 0.02 to 0.04 micrograms parathion per ml. It was concluded that parathion is very slowly absorbed, which makes this compound very unsuitable as a model substance in studies of the process of percutaneous absorption. The results have been discussed with special regard to experimental errors involved and to practical implications.
||Included in PB-280 565,Journal articles on toxicology. Group 12.
||Pub. in Acta Dermato-Venereologica, v41 p353-362 1961.
||Included in the report, Journal Articles on Toxicology, Group 12, PB-280 565.
||Journal articles on toxicology. Group 12.
||Reprint: Studies on the Percutaneous Absorption of Parathion and Paraoxon, III. Rate of Absorption of Parathion,
|PUB Date Free Form
||31 May 61
||6T; 6P; 57Y; 57S; 68E
||(Order as PB-280 565, MF A01)