Main Title |
Diazinon (Trade Name): Chronic Toxicity to, and Brain Acetylcholinesterase Inhibition in, the Sheepshead Minnow, 'Cyprinodon variegatus'. |
Author |
Goodman, Larry R. ;
Hansen, David J. ;
Coppage, David L. ;
Moore, James C. ;
Matthews, Edward ;
|
CORP Author |
Environmental Research Lab., Gulf Breeze, FL. |
Year Published |
1979 |
Report Number |
EPA-600/J-79-071 ;CONTRIB-374; |
Stock Number |
PB80-177736 |
Additional Subjects |
Fishes ;
Toxicology ;
Diazinon ;
Pesticides ;
Insecticides ;
Concentration(Composition) ;
Minnows ;
Phosphorus organic compounds ;
Reprints ;
Toxic substances ;
Water pollution effects(Animals) ;
Cyprinodon variegatus ;
Maximum permissible exposure
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB80-177736 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
13p |
Abstract |
The toxicity of Diazinon to sheepshead minnows is described. Although the number of eggs spawned by continuously exposed fish was significantly reduced (alpha =0.05) in all concentrations, no concentration tested significantly affected parental survival or fertility of eggs, nor were survival and growth of progeny affected in a subsequent 28-day test. Fish exposed to 0.47 micrograms/liter spawned 22.6 eggs/female-day, or 69% of control production (32.8 eggs/female-day). The number of eggs spawned by fish exposed to 6.5, 3.5, 1.8, and 0.98 micrograms/liter Diazinon was similar (14.9-17.9 eggs/female-day), averaging 45-55% of production by control fish. Egg production by fish that had been previously exposed to 3.5 micrograms/liter did not change significantly following depuration for 23 to 31 days. AChE activity varied inversely with exposure concentration, fish in the highest concentration (6.5 micrograms/liter) averaging 71% inhibition. The concentration of Diazinon measured in adult fish exposed to 1.8, 3.5, and 6.5 micrograms/liter averaged 169 times the concentration measured in the water. Diazinon was not consistently detected (<0.05 mg/kg) in fish exposed to 0.98 and 0.47 micrograms/liter. The maximum acceptable toxicant concentration (MATC) for sheepshead minnows continuously exposed to Diazinon, based on reduced fecundity, is <0.47 micrograms/liter; the application factor (MATC divided by 96-hour median lethal concentration) is <0.0003. |
Supplementary Notes |
Pub. in Transactions of American Fisheries Society, v108 p479-488, 1979. |
NTIS Title Notes |
Final rept.. |
Title Annotations |
Reprint: Diazinon (Trade Name): Chronic Toxicity to, and Brain Acetylcholinesterase Inhibition in, the Sheepshead Minnow, 'Cyprinodon variegatus'. |
PUB Date Free Form |
1979 |
Category Codes |
6T; 6F; 57Y; 68E; 68D |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/04 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
323778523 |
Origin |
NTIS |
Type |
CAT |