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RECORD NUMBER: 21 OF 338

OLS Field Name OLS Field Data
Main Title Barium Bioavailability as the Chloride, Sulfate, or Carbonate Salt in the Rat.
Author McCauley, P. T. ; Washington, I. S. ;
CORP Author Health Effects Research Lab., Cincinnati, OH.
Year Published 1983
Report Number EPA-600/J-83-048;
Stock Number PB84-101799
Additional Subjects Barium ; Toxicology ; Rats ; Laboratory animals ; Concentration(Composition) ; Diets ; Ingestion(Biology) ; Biological availability ; Drinking water
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NTIS  PB84-101799 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 11p
Abstract This study was conducted to determine how the bioavailability of a low concentration of barium (Ba) in drinking water is affected by anion speciation. Male Sprague Dawley rats weighing 250-300 grams were maintained on a diet of less than 1 mg Ba/kg of food for at least 1 month prior to experimentation. Rats were given 10.0 mg Ba131/liter as sulfate (SO4), chloride (C1), or carbonate (CO3) at pH 7.0. Animals were sacrificed at 2, 5, 10, 20, 30, 60, and 120 minutes and 24 hours after intubation. When 131Ba was administered, as C1, 131Ba in blood rose linearly for 10 minutes and then less rapidly until the highest number of counts was measured at 60 minutes. At 24 hours 131Ba was still at 90% of peak levels. In eye, 131Ba increased linearly for 1 hour.
Supplementary Notes Pub. in Drug and Chemical Toxicology, v6 n2 p209-217 1983.
NTIS Title Notes Journal article.
PUB Date Free Form 1983
Category Codes 6T; 57Y
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 400621644
Origin NTIS
Type CAT