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RECORD NUMBER: 258 OF 343

OLS Field Name OLS Field Data
Main Title Potentiation of Phosphorus Insecticides by Phenothiazine Derivatives: Possible Hazard, with Report of a Fatal Case.
Author Arterberry, John D. ; Bonifaci, Robert W. ; Nash, Edward W. ; Quinby., Griffith E. ;
CORP Author Communicable Disease Center, Atlanta, Ga.
Year Published 1962
Stock Number PB-280 569; PB-280 565
Additional Subjects Pesticides ; Industrial medicine ; Drugs ; Antidotes ; Phosphates ; Insecticides ; Phosphorus organic compounds ; Cholinesterase inhibitors ; Toxic diseases ; Signs and symptoms ; Therapy ; Pharmacology ; Clinical medicine ; Reprints ; Parathion ; Phosphorothioic acid/O-O-(dimethyl-ester)-O-(nitrophenyl-ester) ; Phosdrin ; Phenothiazines ; Promazine ; Occupational safety and health
Holdings
Library Call Number Additional Info Location Last
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Status
NTIS  PB-280 569 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 3p
Abstract A mentally deficient apple rancher developed moderate signs of organic phosphorus poisoning when his blood cholinesterases were inactivated to near zero after exposure to Phosdrin and parathion. Symptomatic therapy included promazine on the 9th through the 12th days of illness. The patient became more agitated, and some signs of poisoning returned during attempted tranquilization. After about the 8th dose of promazine (Sparine) hydrochloride in 3 days, the patient developed convulsions, hypotension, and apnea, and died. The possible hazard of phenothiazine-derived drugs may outweigh their therapeutic value in the treatment of organic phosphorus poisoning.
Notes Included in PB-280 565, Journal articles on toxicology. Group 12.
Supplementary Notes Pub. in Jnl. of the American Medical Association, v182 p848-850, 24 Nov 62.
Availability Notes Included in the report, Journal Articles on Toxicology, Group 12, PB-280 565.
Alternate Title Journal articles on toxicology. Group 12.
Title Annotations Reprint: Potentiation of Phosphorus Insecticides by Phenothiazine Derivatives: Possible Hazard, with Report of a Fatal Case,
PUB Date Free Form 1962
Category Codes 6T; 6J; 6E; 57Y; 57U; 57E; 68G; 68E
NTIS Prices (Order as PB-280 565, MF A01)
Primary Description 500/01
Document Type NT
Cataloging Source NTIS/MT
Control Number 323740378
Origin NTIS
Type CAT