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RECORD NUMBER: 13 OF 38

OLS Field Name OLS Field Data
Main Title Effects of Hyperthermia and Hyperthermia Plus Microwaves on Rat Brain Energy Metabolism.
Author Sanders, A. P. ; Joines, W. T. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1984
Report Number EPA-600/J-84-024;
Stock Number PB84-204098
Additional Subjects Hyperthermia ; Microwaves ; Radiation effects ; Heat stress ; Rats ; Laboratory animals ; Brain ; Energy ; Metabolism ; Reprints ; ATP ; CP
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB84-204098 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 11p
Abstract The effects of hyperthermia, alone and in conjunction with microwave exposure, on brain energetics were studied in anesthetized male Sprague-Dawley rats. The effects of temperature on adenosine triphosphate concentration (ATP) and creatine phosphate concentration (CP) was determined in the brains of rats that were maintained at 35.6, 37.0, 39.0, and 41.0C brain (ATP) and (CP) were down 6.0, 10.8, and 29.2%, and 19.6, 28.7, and 44%, respectively, from the 35.6C control concentrations. Exposure of the brain to 591-MHz radiation at 13.8 mW/cm sq for 0.5, 1.0, 3.0, and 5.0 min caused further decreases (below those observed for 30C hyperthermia only) of 16.0, 29.8, 22.5, and 12.3% in brain (ATP), and of 15.6, 25.1, 21.4, and 25.9% in brain (CP) after 0.5, 1.0, 3.0, and 5.0 min, respectively. Recording of brain reduced nicotinamide adenine dinucleotide (NADH) fluorescence before, during, and after microwave exposure showed an increase in NADH fluorescence during microwave exposure that returned to preexposure levels within 1 min postexposure.
Supplementary Notes Pub. in Bioelectromagnetics 5, p63-70 1984.
NTIS Title Notes Journal article.
Title Annotations Reprint: Effects of Hyperthermia and Hyperthermia Plus Microwaves on Rat Brain Energy Metabolism.
PUB Date Free Form 1984
Category Codes 6S; 6R; 57W; 57V
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 424417615
Origin NTIS
Type CAT