Main Title |
Initial Submission: Letter from Eastman Kodak Co., to USEPA regarding Toxicity Studies of Chlorosulfuric Acid with Attachments and Cover Letter dated 09/24/1992. |
CORP Author |
Eastman Kodak Co., Rochester, NY.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
Year Published |
1992 |
Report Number |
8EHQ-0992-10619 |
Stock Number |
OTS0570953 |
Additional Subjects |
Toxicology ;
Health effects ;
Toxic substances ;
Chlorosulfuric acid ;
Acute toxicity ;
Mammals ;
Rats ;
Oral ;
Gavage ;
Guinea pigs ;
Dermal ;
Inhalation ;
CAS No 7790-94-5
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Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
OTS0570953 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
35p |
Abstract |
Groups of five male rats and five female rats were exposed to target concentrations of 3400, 2250, 1500, 563, 282, or 70 mg/m(sup 3) chlorosulfonic acid (CSA) for one hour and then held for 14 days of observation. CSA caused clinical signs of respiratory and eye irritation at all but the two lowest exposure concentrations. Mortality was observed during the observation period at the three highest dose levels. Gross and histopathologic changes observed at these dose levels included lung hemorrhage, enlarged livers, pale and small spleens, small thymuses, degenerative and inflammatory changes of the respiratory tract, liver hypertrophy, and degenerative changes in the spleen and thymus. With the exception of clinical signs of respiratory irritation, no treatment-related effects were observed at the three lowest dose levels. The one-hour LCm value was approximately 926 mg/m3. The test material has been used internally and sold as a pure chemical. |
Supplementary Notes |
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Availability Notes |
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PUB Date Free Form |
30 Sep 1992 |
Category Codes |
57Y; 57U; 68G; 99; 44G |
NTIS Prices |
PC A04/MF A04 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
018800360 |
Origin |
NTIS |
Type |
CAT |