Main Title |
Method for the Determination of Dialkyl Phosphate Residues in Urine. |
Author |
Reid, Stuart J. ;
Watts, Randall R. ;
|
CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. Environmental Toxicology Div. |
Year Published |
1981 |
Report Number |
EPA-600/J-81-151; |
Stock Number |
PB82-124264 |
Additional Subjects |
Pesticides ;
Urine ;
Chemical analysis ;
Organic phosphates ;
Exposures ;
Public health ;
Gas chromatography ;
Residues ;
Concentration(Composition) ;
Reprints ;
Phosphoric acid/(dimethyl-ester) ;
Phosphoric acid/(diethyl-ester) ;
Phosphorothionic acid/(dimethyl-ester) ;
Phosphorodithioic acid/(dimethyl-ester) ;
Phosphorthionic acid/(diethyl-ester) ;
Phosphorodithioic acid/(diethyl-ester)
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB82-124264 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
9p |
Abstract |
The analysis of urine for dialkyl phosphate residues provides a measure of mammalian exposure to organophosphate pesticides. A method is presented for quantitative determination of six alkyl phosphate urinary metabolites. These metabolites are as follows: 0,0-dimethyl phosphate, 0,0-diethyl phosphate, 0,0-dimethyl phosphorothionate, 0,0-dimethyl phosphorodithioate, 0,0-diethyl phosphorthionate, and 0,0-diethyl phosphorodithioate. A screening method is also given for a rapid assessment of human exposure. Pentafluorobenzyl bromide is utilized as the derivatization reagent to form pentafluorobenzyl esters. The reaction products are determined by gas chromatography on routine pesticide columns utilizing the phosphorus specific flame photometric detector. Recoveries of all six dialkyl phosphates are greater than 90% with the minimum level of detection ranging from 0.04 to 0.13 ppm. |
Supplementary Notes |
Pub. in Jnl. of Analytical Toxicology, v5, p126-132, May/June 81. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: A Method for the Determination of Dialkyl Phosphate Residues in Urine. |
PUB Date Free Form |
Sep 81 |
Category Codes |
7D; 6E; 68E; 57D; 99A |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
323807289 |
Origin |
NTIS |
Type |
CAT |