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RECORD NUMBER: 93 OF 93

Main Title USEPA Status Report: Pyrazole with Cover Letter dated 08/25/89. (Sanitized).
CORP Author Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher 10 Jul 1989
Year Published 1989
Report Number FYI-OTS-0389-0677S;
Stock Number OTS-0000677-1
Additional Subjects Pyrzole ; Toxicity ; Tests ; Fetus ; Rats ; Gestation ; Dosimitry ; Mice ; Teratology ; CAS No 288-13-1 ; Developmental toxicity ; Embryo toxicology ; Maternal toxicity
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NTIS  OTS-0000677-1 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 12p
Abstract The information presented in the published studies cited in the FYI submission indicates that pyrazole can cause developmentally toxic effects following intraperitoneal injection in mice and oral administration to rats. Giknis and Damjanov (1982) found that intraperitoneal injections of pyrazole at a dose of 6 mg/kg/day to pregnant Swiss Webster mice on days 8, 10, 12 and 14 of gestation resulted in reduced litter size and reduced fetal weight.
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