Main Title |
Initial Submission: Letter from BASF Corp. to USEPA regarding a Prenatal Toxicity Study of Trilon C in Pregnant Wistar Rats by Gavage with Cover Letter dated 07/14/1992. |
CORP Author |
BASF Corp., Mount Olive, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
Year Published |
1992 |
Report Number |
8EHQ-0792-10980 |
Stock Number |
OTS0571018 |
Additional Subjects |
Toxicology ;
Health effects ;
Toxic substances ;
Trilon C ;
Reproduction ;
Fertility effects ;
Teratogenicity ;
Mammals ;
Rats ;
Oral ;
Gavage ;
CAS No 140-01-2
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
OTS0571018 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
6p |
Abstract |
In this full-scale study, aqueous solutions of the test substance were administered to groups of 22 - 23 pregnant Wistar rats by gavage for 10 consecutive days (days 6 - 15 post coitum) in daily doses of 100, 400 and 1,000 mg/kg body weight. For comparison, a control group was dosed with double distilled water. Food consumption and body weights of the animals were recorded regularly throughout the study period. The state of health of the animals was checked daily. On day 20 p.c., all females were sacrificed and assessed by gross pathology. The fetuses were dissected from the uterus, sexed, weighed and further investigated for any external findings. Soft tissue and skeletal examinations of the rat fetuses will be performed after appropriate fixation and/or staining. |
Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
PUB Date Free Form |
22 Jul 1992 |
Category Codes |
57Y; 57U; 68G; 99; 44G |
NTIS Prices |
PC A02/MF A02 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
018800650 |
Origin |
NTIS |
Type |
CAT |