| Main Title |
Initial Submission: Report on Cga 18 809 Tech. Teratology Study in Rabbits (Final Report) with Attachments and Cover Letter Dated 01/07/1992. |
| CORP Author |
CIBA-GEIGY Corp., Toms River, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1992 |
| Report Number |
88-920000590 |
| Stock Number |
OTS0535150 |
| Additional Subjects |
Toxicology ;
Health effects ;
Azamethiphos ;
Reproduction/fertility Effects ;
Teratogenicity ;
Mammals ;
Rabbits ;
Oral ;
Gavage ;
Toxic substances ;
Laboratory animals ;
CAS No 35575-96-3
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0535150 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
62p |
| Abstract |
Azamethiphos (CAS No. 35575-96-3) was evaluated for developmental toxicity. Twenty pregnant rabbits (strain was not reported) per group were treated with 0, 2.5, 7.5, or 15 mg/kg/day of the test material by oral gavage on days 6-18 of gestation. Food consumption and body weight gain were reduced in dams at 7.5 and 15 mg/kg/day. At 15 mg/kg/day, significantly decreased body weight, increased numbers of unossified phalangeal nuclei of the fore and hind-limbs, and unossified 5th sternebrae were observed. These observations were related to maternal toxicity. No embryotoxic or teratogenic effects were observed. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
1992 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A05/MF A05 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028803300 |
| Origin |
NTIS |
| Type |
CAT |
