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OLS Field Name OLS Field Data
Main Title Letter Submitting One Enclosed Teratology Study and One Enclosed Supplementary Study on Isopropanol.
CORP Author British Industrial Biological Research Association, Carshalton (England).; Chemical Manufacturers Association, Washington, DC.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1992
Report Number 86-920000727
Stock Number OTS0535606
Additional Subjects Toxicology ; Health effects ; Isopropanol (67-63-0) ; Reproduction/fertility Effects ; Teratogenicity ; Mammals ; Rats ; Oral ; Diet ; Toxic substances ; Laboratory animals ; CAS No 67-63-0
Library Call Number Additional Info Location Last
NTIS  OTS0535606 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 03/10/2010
Collation 183p
Abstract Isopropanol (CAS No. 67-63-0) was tested for developmental toxicity. The test substance was administered orally in the drinking water at 0, 0.5, 1.25, and 2.5% to pregnant rats (20/group) on gestation days 6-16. The rats were sacrificed on day 20 for examination. Animals in the two highest dose groups had reduced food and water intake, and a decrease in body weight was noted in the 2.5% group. Mean litter weight decreased with increasing concentration, and there was a statistically significant decrease in mean fetal body weight in the two highest groups compared to controls. No evidence of teratogenicity was noted.
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PUB Date Free Form 1992
Category Codes 57Y; 57U; 68G; 99; 44G
NTIS Prices PC A10/MF A10
Document Type NT
Cataloging Source NTIS/MT
Control Number 028803400
Origin NTIS
Type CAT