||Initial Submission: Teratology Study of 3-Chloro-N-(5-Chloro- 2,6-dinitro-4-Trifluoro- Methyl-Phenyl) 5-Trifluoro-Methyl-Pyridinamine in Rats with Cover Letter dated 08/19/1992.
||IIT Research Inst., Chicago, IL. Life Sciences Research Div.; CIBA-GEIGY Corp., Ardsley, NY.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Health effects ;
3-Chloro-N-(5-Chloro- 2 ;
6-Dinitro-4-Trifluoro- Methyl-Phenyl) ;
Fertility effects ;
CAS No 79622-59-6
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||The influence of B-1216 upon the progress and outcome of pregnancy was assessed in sexually mature female rats of the CD strain. For this purpose 8-1216 was administered orally, by gastric intubation in corn oil vehicle, at dosages of 10, 50 or 250 mg/kg/day, to groups of 20 pregnant rats from Day 6 to Day 15 inclusive of gestation. Twenty pregnant control animals received the vehicle only, throughout the same period of gestation and at the same volume dosage (10 m1/kg). All females were killed on Day 20 of gestation for examination of their uterine contents.
||The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
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|PUB Date Free Form
||24 Aug 1992
||57Y; 57U; 68G; 99; 44G
||PC A06/MF A06