||Ventilatory Patterns of Bluegill ('Lepomis macrochirus') Exposed to Organic Chemicals with Different Mechanisms of Toxic Action (Revised).
Carlson, R. W. ;
||Environmental Research Lab.-Duluth, MN.
Water pollution effects(Animals) ;
Chemical water pollutants ;
Freshwater fishes ;
Structure-activity relationship ;
Mucus membranes ;
Cholinesterase inhibitors ;
Electron transport ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||Bluegill (Lepomis macrochirus) were exposed to 13 organic chemicals representing five known toxic mechanisms and their ventilatory patterns examined for differential responses related to mechanism. Two quantifiable characteristics of the ventilatory pattern, ventilatory frequency and cough frequency, had diagnostic utility as clinical signs to differentiate chemicals that killed through narcosis from those that killed by other toxic mechanisms. Bluegill were also exposed to 2-chloroethanol and 2,4-pentanedione, chemicals previously considered as narcotic poisons but tested here as unknowns. Ventilatory patterns induced by these chemicals and time to death in LC100 concentrations support current theories that they kill by mechanisms other than narcosis.
||Pub. in Comparative Biochemistry and Physiology, v95C n2 p181-196 1990.
|NTIS Title Notes
||Reprint: Ventilatory Patterns of Bluegill ('Lepomis macrochirus') Exposed to Organic Chemicals with Different Mechanisms of Toxic Action (Revised).
||68D; 57Y; 57S
||PC A03/MF A01