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OLS Field Name OLS Field Data
Main Title Immunotoxicology strategies for pharmaceutical safety assessment /
Other Authors
Author Title of a Work
Herzyk, Danuta J.
Bussiere, Jeanine L.
Publisher Wiley,
Year Published 2008
OCLC Number 216937167
ISBN 9780470122389 (cloth); 0470122382 (cloth)
Subjects Immunotoxicology. ; Immune system--Effect of drugs on. ; Toxicity testing. ; Drugs--Toxicology. ; Drug Toxicity--immunology. ; Drug Design. ; Drug Evaluation--methods. ; Immune System--drug effects. ; Immunotoxins--adverse effects. ; Risk Assessment. ; Sistema imune. ; Toxicologia. ; Immunpharmakologie. ; Arzneimitteldesign. ; Toxikologie. ; Klinisches Experiment. ; Immunotoxin. ; Arzneimittelnebenwirkung.
Internet Access
Description Access URL
Publisher description http://catdir.loc.gov/catdir/enhancements/fy0829/2008015104-d.html
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EKBM  RC582.17.I47 2008 Research Triangle Park Library/RTP, NC 08/21/2012
Collation xxviii, 402 p., [12] p. of plates : ill. (some col.) ; 25 cm.
Notes Includes bibliographical references and index.
Contents Notes Current regulatory expectations for immunotoxicologyy evaluation of pharmaceuticals / Kenneth L. Hastings -- Clinical pathology as crucial insight into immunotoxicity testing / Ellen Evans -- Histomorphology of the immune system : a basic step in assessing immunotoxicity / Patrick Haley -- Need for specialized immunotoxicity tests / Kazuichi Nakamura -- Specific drug-induced immunotoxicity : immune-mediated hemolytic anemia / Raj Krishnaraj -- T cell-dependent antibody response tests / Joseph R. Piccotti -- Natural killer cell assay and other innate immunity tests / Lisa Plitnick -- Cellular immune response in delayed-type hypersensitivity test / Karen Price -- Evaluation of drug effects on immune cell phenotypes / Laurie Iciek -- Functional cellular responses and cytokine profiles / Elizabeth R. Gore -- Application of flow cytometry in drug development / Padma Narayanan ... [et al.] -- Animal models of host resistance / Gary R. Burleson and Florence G. Burleson -- Approaches to evaluation of autoimmunity / Danuta J. Herzyk -- Differentiating between desired immunomodulation and potential immunotoxicity / Jeanine L. Bussiere and Barbara Mounho -- Relevant immune tests across different species and surrogate models / Jeanine L. Bussiere -- Antidrug antibody responses in nonclinical studies and their implications / Barbara Mounho -- Pharmacological immunogenicity and adverse responses to vaccines / Mary Kate Hart, Mark Bolanowski, and Robert V. House -- Immunotoxicological concerns for vaccines and adjuvants / Catherine Kaplanski ... [et al.] -- Systemic hypersensitivity / Raymond Pieters -- Nonclinical models to assess respiratory hypersensitivity potential / Curtis C. Maier -- Developmental immunotoxicity in rodents / Rodney R. Dietert and Leigh Ann Burns-Naas -- Developmental immunotoxicity in nonhuman primates / Pauline L. Martin and Eberhard Buse -- Alternative animal models for immunomodulation and immunotoxicity / Peter J. Bugelski -- Animal models for preclinical comparative immunogenicity testing / Daniel Wierda -- T cell epitopes and minimization of immunogenicity / Harald Kropshoffer and Thomas Singer -- Bridging immunotoxicology to clinical drug development / Ian Gourley and Jacques Descotes.
Place Published Hoboken, N.J.
PUB Date Free Form c2008
BIB Level m
Cataloging Source OCLC/T
LCCN 2008015104
OCLC Time Stamp 20120806123156
Language eng
Origin OCLC
Type CAT
OCLC Rec Leader 04793cam 22007454a 45020