| Main Title |
Letter from Union Carbide C and P Company, Inc. to US EPA Submitting Studies on Selexol with Attachments. (Sanitized). |
| CORP Author |
Allied Chemical Corp., Morristown, NJ. ;Union Carbide and Carbon Corp., New York.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
21 Aug 1990 |
| Year Published |
1990 |
| Report Number |
FYI-OTS-0990-0769S; |
| Stock Number |
OTS-0000769-1 |
| Additional Subjects |
Toxicology ;
Nervous system ;
Behavior ;
Rats ;
Dose-response relationships ;
Motor activity ;
Laboratory animals ;
Physiology ;
Saline ;
Testing ;
Selexol
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0000769-1 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
146p |
| Abstract |
Selexol (trademark) was evaluated for neurobehavioral effects in male Fischer 344 rats at oral dose levels of 1, 0.1, and 0.01 mL/kg (single dose) and 0.5, 0.25, and 0.1 mL/kg (doses on each of five consecutive days). Each dose group contained four animals. In addition, for both the single dose and repeated sets of groups, a vehicle control group received 1 mL/kg of physiological saline on an identical schedule. All animals were evaluated for motor and sensory reflexes and (by an automated testing system) for impairment of learning and performance of a simple signaled response (SR) motor function. Signs similar to those seen in earlier Selexol studies were observed in the neuromuscular screen. |
| Supplementary Notes |
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| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| Category Codes |
57Y; 57S |
| NTIS Prices |
PC A08/MF A02 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
035500210 |
| Origin |
NTIS |
| Type |
CAT |
