Main Title |
Letter from Union Carbide C and P Company, Inc. to US EPA Submitting Studies on Selexol with Attachments. (Sanitized). |
CORP Author |
Allied Chemical Corp., Morristown, NJ. ;Union Carbide and Carbon Corp., New York.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
Publisher |
21 Aug 1990 |
Year Published |
1990 |
Report Number |
FYI-OTS-0990-0769S; |
Stock Number |
OTS-0000769-1 |
Additional Subjects |
Toxicology ;
Nervous system ;
Behavior ;
Rats ;
Dose-response relationships ;
Motor activity ;
Laboratory animals ;
Physiology ;
Saline ;
Testing ;
Selexol
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
OTS-0000769-1 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
146p |
Abstract |
Selexol (trademark) was evaluated for neurobehavioral effects in male Fischer 344 rats at oral dose levels of 1, 0.1, and 0.01 mL/kg (single dose) and 0.5, 0.25, and 0.1 mL/kg (doses on each of five consecutive days). Each dose group contained four animals. In addition, for both the single dose and repeated sets of groups, a vehicle control group received 1 mL/kg of physiological saline on an identical schedule. All animals were evaluated for motor and sensory reflexes and (by an automated testing system) for impairment of learning and performance of a simple signaled response (SR) motor function. Signs similar to those seen in earlier Selexol studies were observed in the neuromuscular screen. |
Supplementary Notes |
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Availability Notes |
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Category Codes |
57Y; 57S |
NTIS Prices |
PC A08/MF A02 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
035500210 |
Origin |
NTIS |
Type |
CAT |