||Acute Toxicity of Monochlorophenols, Dichlorophenols and Pentachlorophenol in the Mouse.
Borzelleca, J. F. ;
Hayes, J. R. ;
Condie, L. W. ;
Egle, J. L. ;
||Medical Coll. of Virginia, Richmond. Dept. of Pharmacology and Toxicology.;Health Effects Research Lab., Cincinnati, OH.
Laboratory animals ;
Chlorine organic compounds ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||Acute oral LD50 values were determined for 2-, 3-, and 4-chlorophenol; 2,3-, 2,4-, 2,5-, 2,6-, 3,4-, and 3,5 dichlorophenol and pentachlorophenol in male and female mice. LD50 values (mg/kg) ranged from 117 (females) and 177 (males) for pentachlorophenol to 2389 (females) and 2643 (males) for 3,5-dichlorophenol. It was found that 2-chlorophenol and 3-chlorophenol were considerably more toxic than the dichlorophenol series. Values for males and females were generally similar, the major differences being with pentachlorophenol and 2,5-dichlorophenol where in both cases the female LD50 was lower.
||Pub. in Toxicology Letters, v29 n1 p39-42 Dec 85. Sponsored by Health Effects Research Lab., Cincinnati, OH.
|NTIS Title Notes
||Reprint: Acute Toxicity of Monochlorophenols, Dichlorophenols and Pentachlorophenol in the Mouse.
|PUB Date Free Form
||6T; 57Y; 68G
||PC A02/MF A01