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RECORD NUMBER: 458 OF 1173

OLS Field Name OLS Field Data
Main Title Fate of ingested chrysotile asbestos fiber in the newborn baboon /
Author Hallenbeck, William H. ; Patel-Mandlik, Kusum
Other Authors
Author Title of a Work
Patel-Mandlik, Kusum
CORP Author Illinois Univ. at the Medical Center, Chicago. School of Public Health.;Health Effects Research Lab., Cincinnati, OH.
Publisher Environmental Protection Agency, Office of Research and Development, Health Effects Research Laboratory ; For sale by the National Technical Information Service,
Year Published 1978
Report Number EPA/600/1-78/069
Stock Number PB-291 686
OCLC Number 53964648
Subjects Asbestos. ; Serpentine. ; Ingestion.
Additional Subjects Asbestos ; Toxicology ; Bioassay ; Dosage ; Infants ; Primates ; Serpentine ; Diets ; Ingestion(Biology) ; Exposure ; Tables(Data) ; Fibers ; Electron microscopy ; Tissues(Biology) ; Evaluation ; Gastrointestinal system ; Kidney ; Spleen ; Liver ; Pathology ; Potable water ; Baboons ; Drinking water ; Papio anubis ; Water pollution effects(Animals)
Holdings
Library Call Number Additional Info Location Last
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Status
NTIS  PB-291 686 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation viii, 16 pages : illustrations ; 28 cm.
Abstract The objective of this research was to determine if orally administered chrysotile asbestos fibers could penetrate through the gastrointestinal tract of the neonate baboon and be recovered in selected tissues. A neonate baboon was given a cumulative dose of 3 to the 13th power chrysotile fibers per kilogram. At the end of a 9-day feeding period test and control animals were sacrificed. The following tissues were collected: kidney, liver, spleen, heart, lymph nodes, urine, blood, and gastrointestinal tract. Many methodological problems were encountered in preparing tissues for evaluation by electron microscopy. After developing a satisfactory preparation technique, tissue samples of kidney cortex, kidney medulla, spleen, and liver were analyzed. Definitive data are presented which demonstrate the recovery of chrysotile asbestos from kidney cortex tissue. Data concerning the kidney medulla, spleen and liver tissues must be considered preliminary as more definitive work is in progress concerning these and other tissues.
Notes Order no. CA-7-3159-J. Dec. 1978. Includes bibliographical references. Microfiche.
Place Published Cincinnati, Ohio :
Corporate Au Added Ent University of Illinois at the Medical Center. School of Public Health. ; Health Effects Research Laboratory (Cincinnati, Ohio)
Corp Au Ser Add Ent Environmental health effects research series ; EPA-600/1-78-069. United States. ; Environmental health effects research series ; EPA-600/1-78-069. United States. ; Environmental health effects research series ; EPA-600/1-78-069. United States.
PUB Date Free Form 1978 i.e. 1979.
Series Title Untraced Environmental health effects research series ; EPA-600/1-78-069
NTIS Prices PC A03/MF A01
BIB Level m
Cataloging Source OCLC/T
OCLC Time Stamp 20031230120425
Language eng
Origin OCLC
Type MERGE
OCLC Rec Leader 01564nam 2200349Ka 45020