| Main Title |
Teratogenic Evaluation of Ethylene Chlorhydrin (ECh, 2-Chlorethanol) in Mice. |
| Author |
Courtney, K. Diane ;
Andrews, James E. ;
Grady, Margaret ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1982 |
| Report Number |
EPA-600/J-82-122; |
| Stock Number |
PB82-247164 |
| Additional Subjects |
Evaluations ;
Mice ;
Laboratory animals ;
Ingestion(Biology) ;
Dosage ;
Chlorine organic compounds ;
Environmental surveys ;
Reprints ;
Ethanol/chloro ;
Teratogenesis
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB82-247164 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
13p |
| Abstract |
ECh administered intragastrically to pregnant CD-1 mice from the 6th to the 16th day of gestation at a dose of 100 mg/kg produced a significant reduction in maternal weight gain and a decrease in fetal body weight and liver weight. A lower dose of 50 mg/kg had no consistent effect and a higher dose of 150 mg/kg was maternally lethal. Administration of ECh in the drinking water at doses of 16, 43, 77, or 227 mg/kg did not produce any adverse effects on maternal or fetal body weight, viability, or fetal development. |
| Availability Notes |
Pub. in Jnl. of Environmental Science and Health B17, n4 p381-391 1982. |
| NTIS Title Notes |
Final rept.. |
| Title Annotations |
Reprint: Teratogenic Evaluation of Ethylene Chlorhydrin (ECh, 2-Chlorethanol) in Mice. |
| PUB Date Free Form |
c1982 |
| Category Codes |
6T; 57Y; 68 |
| NTIS Prices |
Not available NTIS |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
323821717 |
| Origin |
NTIS |
| Type |
CAT |
