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RECORD NUMBER: 300 OF 339

OLS Field Name OLS Field Data
Main Title Study of Chlorine Dioxide and its Metabolites in Man.
Author Bianchine, Joseph R. ; Lubbers, Judith R. ; Chauhan, Sudha ; Miller, Judy ;
CORP Author Ohio State Univ., Columbus. Coll. of Medicine.;Health Effects Research Lab., Cincinnati, OH.
Year Published 1981
Report Number EPA-805643; EPA-600/1-81-068;
Stock Number PB82-109356
Additional Subjects Disinfectants ; Toxicology ; Physiological effects ; Chlorine oxide(ClO2) ; Metabolites ; Toxic substances
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB82-109356 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 100p
Abstract To assist in the assessment of the relative safety of chronically administered chlorine water disinfectants in man, a controlled study was undertaken. The study was conducted in three phases. Phase I, a rising dose tolerance investigation, examined the effects of single dose increasing concentration administration of chlorine disinfectants to normal healthy adult male volunteers. Phase II considered the impact on normal subjects of twelve week daily ingestion of the disinfectants at a concentration of 5 mg/L. In phase III, chlorite, at a concentration of 5 mg/L, was administered daily to glucose-6-phosphate dehydrogenase deficient subjects. Physiological impact was assessed by evaluation of a large battery of qualitative and quantitative tests. In general, the study affirmed the relative safety and tolerance of normal healthy adult males and normal healthy adult male G-6-PD deficient individuals to daily twelve week ingestion of 500 mL of chlorine disinfectants at a concentration of 5 mg/L.
PUB Date Free Form Sep 81
Category Codes 6T; 6E; 57Y; 57O
NTIS Prices PC A05/MF A01
Primary Description 600/10
Document Type NT
Cataloging Source NTIS/MT
Control Number 323805628
Origin NTIS
Type CAT