Main Title |
Alteration of Cellular Interactions in the Immune System: Natural Killer Activity and N Lymphocytes. |
Author |
Burleson, G. R. ;
|
CORP Author |
Northrop Services, Inc., Research Triangle Park, NC.;Health Effects Research Lab., Research Triangle Park, NC. |
Year Published |
1987 |
Report Number |
EPA-68-02-4450; EPA/600/D-87/302; |
Stock Number |
PB88-106414 |
Additional Subjects |
Immunology ;
Neoplasms ;
Viral diseases ;
Lymphocytes ;
Killer cells(Natural) ;
Immune system ;
Suppressor cells ;
NK(Natural killer)
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB88-106414 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
56p |
Abstract |
N lymphocytes, like interferons, have three major biological functions: (1) antitumor activity; (2) antiviral activity; and (3) immunoregulatory activity. Antitumor activity is also referred to as natural killer (NK) activity which represents the non-MHC-restricted lysis of NK-sensitive tumor cells by effector cells obtained from a nonimmunized host. N lymphocytes play a pivotal role in a network of immune functions. The review discusses the (1) properties of natural killer activity, (2) importance of natural killer activity against tumor cells, (3) importance of N lymphocytes in viral infections, (4) regulation of natural killer activity by cytokines, (5) alteration of natural killer activity by suppressor cells, and (6) alteration of natural killer activity by chemicals. |
Supplementary Notes |
Sponsored by Health Effects Research Lab., Research Triangle Park, NC. |
PUB Date Free Form |
Sep 87 |
Category Codes |
57J; 57E |
NTIS Prices |
PC A04/MF A01 |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
735120872 |
Origin |
NTIS |
Type |
CAT |