Main Title |
Poly(ADP-Ribosyl)ation [electronic resource] / |
Type |
EBOOK |
Author |
Bürkle, Alexander.
|
Publisher |
Springer US, |
Year Published |
2006 |
Call Number |
QR46 |
ISBN |
9780387360058 |
Subjects |
Medicine ;
Human genetics ;
Microbiology ;
Biochemistry ;
Cytology
|
Internet Access |
|
Collation |
XVII, 246 p. online resource. |
Notes |
Due to license restrictions, this resource is available to EPA employees and authorized contractors only |
Contents Notes |
Enzymes in Poly(ADP-Ribose) Metabolism -- PARP-2: Structure-Function Relationship -- Targeting the Poly (ADP-Ribose) Glycohydrolase (PARG) Gene in Mammals -- DNA Damage Signaling through Poly(ADP-Ribose) -- Roles of Poly(ADP-Ribose) Metabolism in the Regulation of Centrosome Duplication and in the Maintenance of Neuronal Integrity -- Functional Interactions of PARP-1 with p53 -- Dynamic Interaction between PARP-1, PCNA and p21waf1/cip1 -- PARP-1 as Novel Coactivator of NF-?B in Inflammatory Disorders -- PARP and Epigenetic Regulation -- PARP and the Release of Apoptosis-Inducing Factor from Mitochondria -- Genome Degradation by DNAS1L3 Endonuclease -- NAD: Metabolism and Regulatory Functions -- PARP-1 and the Shape of Cell Death -- Poly(ADP-Ribose) Polymerase (PARP) and Excitotoxicity -- Poly(ADP-Ribose) Polymerase and Ischemia-Reperfusion Injury -- Role of Poly(ADP-Ribose) Polymerase Activation in the Pathogenesis of Inflammation and Circulatory Shock -- Role of Poly-ADP-Ribosylation in Cancer Development -- PARP Inhibitors and Cancer Therapy -- Poly(ADP-Ribosyl)ation and Aging. Poly(ADP-Ribosyl)ation comprises 19 chapters written by leading international experts in the field and is richly illustrated. Extensive bibliography is given in each chapter. |
Place Published |
Boston, MA |
Corporate Au Added Ent |
SpringerLink (Online service) |
Title Ser Add Ent |
Molecular Biology Intelligence Unit |
Host Item Entry |
Springer eBooks |
PUB Date Free Form |
2006 |
Series Title Untraced |
Molecular Biology Intelligence Unit |
BIB Level |
m |
Medium |
computer |
Content |
text |
Carrier |
online resource |
Cataloging Source |
OCLC/T |
OCLC Time Stamp |
20131219115954 |
Language |
eng |
Origin |
SPRINGER |
Type |
EBOOK |
OCLC Rec Leader |
02771nam a22004935i 45 |